Probation qualifications framework: Getting the right balance

Getting the Fluid Balance Right in Malaria

There is a much-quoted saying, attributed to the epidemiologist Geoffrey Rose: “A large number of people exposed to a small risk may generate many more cases than a small number exposed to a very high risk.” This is true for many individual risk factors such as salt intake (linked to high blood pressure and cardiovascular disease) and speeding on the highway (linked to injuries and accidents). ...

Iron nutrition in the UK: getting the balance right.

Fe homeostasis is considered in the context of the UK diet, using information on Fe intake and status from the National Diet and Nutrition Surveys. The importance of assessing Fe availability rather than total Fe intake is discussed. Dietary and host-related factors that determine Fe bioavailability (Fe utilised for Hb production) are reviewed using information from single-meal studies. When ad...

Stress and exercise: Getting the balance right for aging immunity.

Age-related immunological and endocrinological changes may have implications for resilience to stress in older adults. We hypothesize that the combination of adrenopause and immunosenescence may leave this population particularly vulnerable to the negative effects of stress on immunity. We propose that exercise may be an effective intervention to limit the impact of stress on immunity in chroni...

Getting the right balance: insole design alters the static balance of people with diabetes and neuropathy

BACKGROUND Over 1 in 3 older people with diabetes sustain a fall each year. Postural instability has been identified as independent risk factor for falls within people with Diabetic Peripheral Neuropathy (DPN). People with DPN, at increased risk of falls, are routinely required to wear offloading insoles, yet the impact of these insoles on postural stability and postural control is unknown. The...

Incentives for Service Quality: Getting the Framework Right